Osteoclast
The osteoclasts are multinucleate cells having 10 to 15 cores (Syncytium) of hematopoietic origin. They have a diameter of 50 with 100µm. The cells myéloïdes are different in promonocytes to then give rise to: - dendritic cells - monocytes (then macrophasges by fusion of the monocytes) - pre-osteoclasts (then osteoclasts by fusion of pre-osteoclasts)
The osteoclasts are the cells responsible for the osseous resorption, on the one hand by decreasing the pH in contact with the osseous matrix, on the other hand by secreting proteolytic enzymes, which brings the degradation of the seuse screen Os.
This osteoclastic activity is permanent and necessary to the maintenance of osseous solidity, in synergy with the activity of the Ostéoblaste S.
the osteoclasts are present in bone tissues in voice of resorption.
See too
- Os
- Ostéocyte
- Collagenous
- Ostein
- Hydroxyapatite
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