Diméthylaminoéthanol

DMAE (diméthylaminoéthanol, déanol), chemically the 2 (diméthylamino) ethanol, is a natural substance connected with the Choline. The DMAE facilitates the synthesis of the Neurotransmetteur Acétylcholine in the Cerveau and would also stimulate the synthesis of Phosphatidylcholine.

One finds some in the Poisson S. It has effects Nootropique S, and, contrary to choline itself, crosses the barrier blood-brain immediately. It is supposed that the DMAE is methylated out of choline in the brain. The DMAE is transformed into choline by the Foie but the choline molecule is too large to pass the barrier blood-brain easily.

Uses

Anti-aging:

Certain studies of short term show that the use of DMAE allows an increase in vigilance and a positive effect on mood whereas other studies moreover long run arrive at different conclusions.

Experiments show an increase in the lifespan in the animal whereas others arrive at a reduction of the average lifespan. Taking into account uncertainty relating to the extrapolation of these results at the man, a contribution of DMAE is generally not recommended. It is possible that proportioning is a major factor of the effect of the DMAE, a strong proportioning could produce the opposite effect with that desired.

Other studies show that the DMAE reduces the accumulation of deposit of Lipofuscine in the cells.

Cosmetic:

One uses the DMAE in industry Cosmétique because it has a light effect hardening and tensor on the skin whose origin is not well-known. This effect could be due to a stabilization of the membranes, with an increase in Acétylcholine, with a reduction of the deposits of lipofuscine or with any of these reasons. The DMAE cannot erase facial fading but can reduce its progression. It seems that the effects are more outstanding with a use on the long run.

2007/04/12 According to the scientific magazine British Newspaper off Dermatology, François Marceau, professor at the medical college of the Laval University noted that the contact between the DMAE and the cutaneous cells called fibroblasts makes inflate the cells quickly. With the swelling of the skin, wrinkles and ridules grow blurred time that the action of DMAE lasts.

Healthy or unhealthy? In their in vitro tests, the researchers noted that swelling causes “an important deceleration of the cellular division” and the “death of a significant percentage of fibroblasts”, write. Twenty-four hours after an application being connected to a normal application of anti-wrinkle cream, death rate reached the quarter of the studied cells.

Taking into account the strong media exposure of the DMAE, many companies of cosmetics the products containing DMAE at ransom price propose. However, the DMAE is a simple substance not more expensive than AHA or the Aspirine. Moreover, the DMAE does not require particular stabilization, like the Vitamine C for example, and it is easy to integrate it into a Excipient. From a purely economic point of view, a cream with the DMAE should not cost more than 5 euros.

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