The carcinome hépatocellulaire (CHC), or hepatocarcinomist, is a primitive cancer of the liver.

Epidemiology

It is the 8th cancer in the world by the most frequent order of frequency and of primitive cancers of the Foie. Its incidence particularly increased these twenty last years because of the increase in the incidence of the Cirrhose due to the virus of the Hépatite C.

It almost always occurs on a preexistent hepatic disease, exceptionally on a healthy liver: cirrhosis in more than 90% of the cases and more rarely noncirrhotic, generally viral chronic hepatopathy (chronic hepatitis C).

Causes

Carcinome hépatocellulaire is thus most of the time a complication of a hepatic disease already present, it exists thus two diseases, a précancéreux cancer and state; this characteristic conditions the forecast and the therapeutic step because it is necessary to take into account the two affections at the same time.

The CHC develops starting from a hearth initial localized then invades the vessels doors and metastasis in the liver itself via the branches portales, which often explains the character multiloculaire cancer and the tendency to the neoplasic thrombosis of the branches then trunk of the portal vein.

Forecast

The forecast gobal is bad, the median of survival is of a few months even if a small proportion of the patients can hope for a better survival.

Treatment

The choice of the treatment is done primarily according to the gravity of the subjacent Hépatopathie and the tumoral extension.

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